SBI-0206965
Product Specifications
CAS Number
1884220-36-3
Target
Autophagy
Applications
Autophagy
Smiles
CNC (=O) C1=CC=CC=C1OC2=NC (=NC=C2Br) NC3=CC (=C (C (=C3) OC) OC) OC
Molecular Formula
C21H21BrN4O5
Additionnal Information
SBI-0206965 is a highly selective autophagy kinase ULK1 inhibitor with IC50 of 108 nM, about 7-fold selectivity over ULK2. SBI-0206965 inhibits autophagy and enhances apoptosis in human glioblastoma and lung cancer cells.
Storage Conditions
2 years -80 in solvent
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