Nazartinib (EGF816)
Product Specifications
CAS Number
1508250-71-2
Synonyms
NVS-816
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
CC1=NC=CC (=C1) C (=O) NC2=NC3=C (N2C4CCCCN (C4) C (=O) C=CCN (C) C) C (=CC=C3) Cl
Molecular Formula
C26H31ClN6O2
Additionnal Information
Nazartinib (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (L858R, ex19del) and T790M mt, with up to 60-fold selectivity over wild type (wt) EGFR in vitro.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
63700 50 Devices
Stool Nucleic Acid Collection and Preservation System (50)
Sign In for Pricing
View Details