Nazartinib (EGF816)
Product Specifications
CAS Number
1508250-71-2
Synonyms
NVS-816
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
CC1=NC=CC (=C1) C (=O) NC2=NC3=C (N2C4CCCCN (C4) C (=O) C=CCN (C) C) C (=CC=C3) Cl
Molecular Formula
C26H31ClN6O2
Additionnal Information
Nazartinib (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (L858R, ex19del) and T790M mt, with up to 60-fold selectivity over wild type (wt) EGFR in vitro.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC940253-500 1x 500 µL
Cytokeratin, LMW (AE-1), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680031-100 1x 100 µL
Mucin 5AC (MUC5AC) (45M1), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC681429-100 1x 100 µL
E-Cadherin / CD324 (Intercellular Junction Marker) (4A2), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details