A-1331852

Product Specifications

CAS Number

1430844-80-6

Target

Bcl-2

Applications

Apoptosis

Smiles

CC1=C (C=NN1CC23CC4CC (C2) CC (C4) C3) C5=C (N=C (C=C5) N6CCC7=C (C6) C (=CC=C7) C (=O) NC8=NC9=CC=CC=C9S8) C (=O) O

Molecular Formula

C38H38N6O3S

Additionnal Information

A-1331852 is a potent and selectiveBCL-XL inhibitor with Ki value less than 0.01 nM for BCL-XL and 6 nM, 4 nM, 142 nM for Bcl-2, Bcl-W, MCL-1 respectively. It may be useful in the treatment of cancer, immune and autoimmune diseases.

Storage Conditions

2 years -80 in solvent

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