Pexmetinib
Product Specifications
CAS Number
945614-12-0
Synonyms
ARRY-614
Target
P38 MAPK
Applications
MAPK
Smiles
CC1=CC=C (C=C1) N2C (=CC (=N2) C (C) (C) C) NC (=O) NCC3=C (C=CC (=C3) F) OC4=CC5=C (C=C4) N (N=C5) CCO
Molecular Formula
C31H33FN6O3
Additionnal Information
Pexmetinib is a potent, orally bioavailable, dual p38 MAPK/Tie-2 inhibitor with IC50 of 4 nM/18 nM in a HEK-293 cell line. Phase 1.
Storage Conditions
2 years -80 in solvent
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