A-1210477
Product Specifications
CAS Number
1668553-26-1
Target
Bcl-2
Applications
Apoptosis
Smiles
CC1=NN (C (=C1C2=CC=CC3=C2N (C (=C3CCCOC4=CC=CC5=CC=CC=C54) C (=O) O) CCN6CCOCC6) COC7=CC=C (C=C7) N8CCN (CC8) S (=O) (=O) N (C) C) C
Molecular Formula
C46H55N7O7S
Additionnal Information
A-1210477 is a potent and selective MCL-1 inhibitor with Ki and IC50 of 0.454 nM and 26.2 nM, respectively, >100-fold selectivity over other Bcl-2 family members.
Storage Conditions
2 years -80 in solvent
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