Gilteritinib (ASP2215)
Product Specifications
CAS Number
1254053-43-4
Target
FLT3
Applications
Protein Tyrosine Kinase
Smiles
CCC1=C (N=C (C (=N1) C (=O) N) NC2=CC (=C (C=C2) N3CCC (CC3) N4CCN (CC4) C) OC) NC5CCOCC5
Molecular Formula
C29H44N8O3
Additionnal Information
Gilteritinib (ASP2215) is a small-molecule FLT3/AXL inhibitor with IC50 values of 0.29 nM and 0.73 nM for FLT3 and AXL, respectively. It inhibits FLT3 at an IC50 value that was approximately 800-fold more potent than the concentration required to inhibit c-KIT (230 nM) .
Storage Conditions
2 years -80 in solvent
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