Ro-3306
Product Specifications
CAS Number
872573-93-8
Target
CDK
Applications
Cell Cycle
Smiles
C1=CC2=C (C=CC (=C2) C=C3C (=O) NC (=NCC4=CC=CS4) S3) N=C1
Molecular Formula
C18H13N3OS2
Additionnal Information
RO-3306 is an ATP-competitive, and selective CDK1 inhibitor with Ki of 20 nM, >15-fold selectivity against a diverse panel of human kinases. RO-3306 enhances p53-mediated Bax activation and mitochondrial apoptosis.
Storage Conditions
2 years -80 in solvent
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