VX-11e

Product Specifications

CAS Number

896720-20-0

Synonyms

VTX-11e, Vertex-11e

Target

ERK

Applications

MAPK

Smiles

CC1=CN=C (N=C1C2=CNC (=C2) C (=O) NC (CO) C3=CC (=CC=C3) Cl) NC4=C (C=C (C=C4) F) Cl

Molecular Formula

C24H20Cl2FN5O2

Additionnal Information

VX-11e (VTX-11e, Vertex-11e) is a potent, selective, and orally bioavailable ERK inhibitor with IC50 of 17 nM (ERK1) and 15 nM (ERK2), over 200-fold selective over other kinases tested.

Storage Conditions

2 years -80 in solvent

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