A-83-01
Product Specifications
CAS Number
909910-43-6
Target
TGF-beta/Smad
Applications
TGF-beta/Smad
Smiles
CC1=NC (=CC=C1) C2=NN (C=C2C3=CC=NC4=CC=CC=C34) C (=S) NC5=CC=CC=C5
Molecular Formula
C25H19N5S
Additionnal Information
A-83-01 is a potent inhibitor of TGF-β type I receptor (ALK5-TD) with IC50 of 12 nM. A-83-01 also inhibits the transcription induced by activin/nodal type I receptor (ALK4-TD) and nodal type I receptor (ALK7-TD) with IC50 of 45 nM and 7.5 nM, respectively.Solutions are unstable and should be fresh-prepared.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
E-UNEL-H0012-01 5x 96 Tests
Uncoated Human ApoB (Apolipoprotein B) ELISA Kit
Sign In for Pricing
View Details E-UNEL-H0012-02 15x 96 Tests
Uncoated Human ApoB (Apolipoprotein B) ELISA Kit
Sign In for Pricing
View Details 
BNC881059-500 1x 500 µL
CD71 (TFRC/1059), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC401118-500 1x 500 µL
Beta-2-Microglobulin (B2M) (B2M/1118), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details