PIK-III
Product Specifications
CAS Number
1383716-40-2
Synonyms
VPS34-IN2
Target
Autophagy
Applications
Autophagy
Smiles
C1CC1CC2=NC (=NC=C2C3=NC (=NC=C3) NC4=CC=NC=C4) N
Molecular Formula
C17H17N7
Additionnal Information
PIK-III (VPS34-IN2), which is a selective inhibitor of VPS34 enzymatic activity, inhibits autophagy and de novo lipidation of LC3 and leads to the stabilization of autophagy substrates. The IC50 values for VPS34 and PI (3) Kδ are 0.018 μM and 1.2 μM respectively.
Storage Conditions
2 years -80 in solvent
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