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Savolitinib (AZD6094)

Product Specifications

CAS Number

1313725-88-0

Synonyms

HMPL-504, Volitinib

Target

C-Met

Applications

Protein Tyrosine Kinase

Smiles

CC (C1=CN2C=CN=C2C=C1) N3C4=NC (=CN=C4N=N3) C5=CN (N=C5) C

Molecular Formula

C17H15N9

Additionnal Information

Savolitinib (Volitinib, AZD6094, HMPL-504) is a novel, potent, and selective MET inhibitor currently in clinical development in various indications, including PRCC. The IC50 values of this compound for c-Met and p-Met are 5 nM and 3 nM, respectively. It shows exquisite selectivity for c-Met over 274 kinase.

Storage Conditions

2 years -80 in solvent

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