Picropodophyllin (PPP)
Product Specifications
CAS Number
477-47-4
Synonyms
AXL1717
Target
IGF-1R
Applications
Protein Tyrosine Kinase
Smiles
COC1=CC (=CC (=C1OC) OC) C2C3C (COC3=O) C (C4=CC5=C (C=C24) OCO5) O
Molecular Formula
C22H22O8
Additionnal Information
Picropodophyllin (PPP, AXL1717) is a IGF-1R inhibitor with IC50 of 1 nM. It displays selectivity for IGF-1R and does not coinhibit tyrosine phosphorylation the IR, or of a selected panel of receptors less related to IGF-IR (FGF-R, PDGF-R, OR EGF-R) . Picropodophyllin (PPP) induces apoptosis with antineoplastic activity.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![BMP8B Mouse Monoclonal Antibody [Clone ID: AT13E6]](https://cdn.genprice.uk/products/937/68dd189e061270361e8fd90d/imageurl/am50356pu-n.webp)
AM50356PU-N 100 µL
BMP8B Mouse Monoclonal Antibody [Clone ID: AT13E6]
Sign In for Pricing
View Details 
![SLC1A5 Recombinant Rabbit Monoclonal Antibody [PSH07-74]](https://cdn.genprice.uk/products/992/68dd1c90061270361ea82981/imageurl/ha722890.webp)
HA722890 100 µL
SLC1A5 Recombinant Rabbit Monoclonal Antibody [PSH07-74]
Sign In for Pricing
View Details 
E-EL-R0792-01 24 Tests
Rat PTGS2/COX-2 (Prostaglandin Endoperoxide Synthase 2) ELISA Kit
Sign In for Pricing
View Details E-EL-R0792-02 48 Tests
Rat PTGS2/COX-2 (Prostaglandin Endoperoxide Synthase 2) ELISA Kit
Sign In for Pricing
View Details E-EL-R0792-03 96 Tests
Rat PTGS2/COX-2 (Prostaglandin Endoperoxide Synthase 2) ELISA Kit
Sign In for Pricing
View Details