What is the catalog number for OTS964?

The catalog number for OTS964 is S7648-100mg.

What sizes are available for OTS964?

OTS964 is available in the following size(s): 100 mg.

OTS964 is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for OTS964?

OTS964 is requires dry ice shipping.

Who manufactures OTS964?

OTS964 is manufactured by Bimake.

What is the estimated delivery time for OTS964?

Estimated delivery time for OTS964 is approximately 15 business day(s), depending on your location.

OTS964

Product Specifications

CAS Number

1338545-07-5

Target

TOPK

Applications

MAPK

Smiles

CC1=CC (=C (C2=C1NC (=O) C3=C2C=CS3) C4=CC=C (C=C4) C (C) CN (C) C) O.Cl

Molecular Formula

C23H24N2O2S.HCl

Additionnal Information

OTS964 is a potent TOPK inhibitor with high affinity and selectivity and IC50 value is 28 nM. OTS964 is also a potent inhibitor of the cyclin-dependent kinase CDK11 with Kd of 40 nM. OTS964 treatment activates autophagy in glioma cells and induces apoptosis of human lung cancer cells in mouse xenografts.