Lucitanib (E3810) hydrochloride
Product Specifications
CAS Number
1058137-23-7
Synonyms
AL3810
Target
FGFR
Applications
Protein Tyrosine Kinase
Smiles
[Cl-].CNC (=O) C1=CC=CC2=C1C=CC (=C2) OC3=CC=NC4=CC (=C (OC) C=C34) OCC5 ([NH3+]) CC5
Molecular Formula
C26H26ClN3O4
Additionnal Information
Lucitanib (E-3810, AL3810) hydrochloride is a dual inhibitor of Vascular endothelial growth factor receptor (VEGFR) and Fibroblast growth factor receptor (FGFR) . Lucitanib hydrochloride (E-3810, AL3810) potently and selectively inhibits VEGFR1, VEGFR2, VEGFR3, FGFR1 and FGFR2 with IC50 of 7 nM, 25 nM, 10 nM, 17.5 nM, and 82.5 nM, respectively.
Storage Conditions
3 years -20°C powder
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