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GW4869

Product Specifications

CAS Number

6823-69-4

Synonyms

GW69A, GW554869A

Target

Phospholipase (e.g. PLA)

Applications

Metabolism

Smiles

C1CN=C (N1) C2=CC=C (C=C2) NC (=O) C=CC3=CC=C (C=C3) C=CC (=O) NC4=CC=C (C=C4) C5=NCCN5.Cl.Cl

Molecular Formula

C30H28N6O2.2HCl.XH2O

Additionnal Information

GW4869 (GW69A, GW554869A) is a neutral, noncompetitive inhibitor of sphingomyelinase (SMase) with an IC50 of 1 μM. It is selective for N-SMase, and does not inhibit acid SMase at up to at least 150 μM, also is a commonly used exosome inhibitor.

Storage Conditions

2 years -80 in solvent

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