Domatinostat (4SC-202)
Product Specifications
CAS Number
910462-43-0
Target
HDAC
Applications
DNA Damage/DNA Repair
Smiles
CN1C=C (C=N1) C2=CC=C (C=C2) S (=O) (=O) N3C=CC (=C3) C=CC (=O) NC4=CC=CC=C4N
Molecular Formula
C23H21N5O3S
Additionnal Information
Domatinostat (4SC-202) is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. Also displays inhibitory activity against Lysine specific demethylase 1 (LSD1) . Phase 1.
Storage Conditions
2 years -80 in solvent
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