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THZ1 2HCl

Product Specifications

CAS Number

2095433-94-4

Target

CDK

Applications

Cell Cycle

Smiles

CN (C) CC=CC (=O) NC1=CC=C (C=C1) C (=O) NC2=CC=CC (=C2) NC3=NC=C (C (=N3) C4=CNC5=CC=CC=C54) Cl

Molecular Formula

C31H30Cl3N7O2

Additionnal Information

THZ1 is a covalent CDK7 inhibitor which has the unprecedented ability to target a remote cysteine residue located outside of the canonical kinase domain, providing an unanticipated means of achieving selectivity for CDK7.

Storage Conditions

2 years -80 in solvent

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