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Decernotinib (VX-509)

Product Specifications

CAS Number

944842-54-0

Target

JAK

Applications

Angiogenesis

Smiles

CCC (C) (C (=O) NCC (F) (F) F) NC1=NC (=NC=C1) C2=CNC3=C2C=CC=N3

Molecular Formula

C18H19F3N6O

Additionnal Information

Decernotinib (VX-509) is a potent and selective JAK3 inhibitor with Ki of 2.5 nM, >4-fold selectivity over JAK1, JAK2, and TYK2, respectively. Phase 2/3.

Storage Conditions

2 years -80 in solvent

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