(S) -crizotinib
Product Specifications
CAS Number
1374356-45-2
Target
MTH1
Applications
DNA Damage/DNA Repair
Smiles
CC (C1=C (C=CC (=C1Cl) F) Cl) OC2=C (N=CC (=C2) C3=CN (N=C3) C4CCNCC4) N
Molecular Formula
C21H22Cl2FN5O
Additionnal Information
(S) -crizotinib, the (S) -enantiomer of crizotinib, is a potent MTH1 (NUDT1) inhibitor with IC50 of 72 nM in a cell-free assay.
Storage Conditions
2 years -80 in solvent
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