FTI 277 HCl
Product Specifications
CAS Number
180977-34-8
Target
Transferase
Applications
Metabolism
Smiles
COC (=O) C (CCSC) NC (=O) C1=C (C=C (C=C1) NCC (CS) N) C2=CC=CC=C2.Cl
Molecular Formula
C22H30ClN3O3S2
Additionnal Information
FTI 277 HCl is a potent and selective farnesyltransferase (FTase) inhibitor with IC50 of 500 pM, about 100-fold selectivity over the closely related GGTase I. FTI 277 HCl inhibits cell growth and induces apoptosis. FTI 277 HCl is effective in clearing HDV viremia.
Storage Conditions
2 years -80 in solvent
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