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PI-1840

Product Specifications

CAS Number

1401223-22-0

Target

Proteasome

Applications

Proteases

Smiles

CCCC1=CC=C (C=C1) OCC (=O) N (CC2=NC (=NO2) C3=CN=CC=C3) C (C) C

Molecular Formula

C22H26N4O3

Additionnal Information

PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor with IC50 of 27 nM with little effects on the other two major proteasome proteolytic activities, trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L) .

Storage Conditions

2 years -80 in solvent

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