What is the catalog number for Resatorvid (TAK-242)?

The catalog number for Resatorvid (TAK-242) is S7455-10mM/1mL.

What sizes are available for Resatorvid (TAK-242)?

Resatorvid (TAK-242) is available in the following size(s): 10 mM/1mL.

Is Resatorvid (TAK-242) in stock?

Resatorvid (TAK-242) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Resatorvid (TAK-242)?

Resatorvid (TAK-242) is manufactured by Bimake.

What is the estimated delivery time for Resatorvid (TAK-242)?

Estimated delivery time for Resatorvid (TAK-242) is approximately 15 business day(s), depending on your location.

Resatorvid (TAK-242)

Product Specifications

CAS Number

243984-11-4

Synonyms

CLI-095

Target

TLR

Applications

Immunology & Inflammation

Smiles

CCOC (=O) C1=CCCCC1S (=O) (=O) NC2=C (C=C (C=C2) F) Cl

Molecular Formula

C15H17ClFNO4S

Additionnal Information

Resatorvid (TAK-242, CLI-095) is a small-molecule-specific inhibitor of Toll-like receptor (TLR) 4 signaling, blocking LPS-induced production of NO, TNF-α and IL-6 in macrophages with IC50 of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy.