Resatorvid (TAK-242)
Product Specifications
CAS Number
243984-11-4
Synonyms
CLI-095
Target
TLR
Applications
Immunology & Inflammation
Smiles
CCOC (=O) C1=CCCCC1S (=O) (=O) NC2=C (C=C (C=C2) F) Cl
Molecular Formula
C15H17ClFNO4S
Additionnal Information
Resatorvid (TAK-242, CLI-095) is a small-molecule-specific inhibitor of Toll-like receptor (TLR) 4 signaling, blocking LPS-induced production of NO, TNF-α and IL-6 in macrophages with IC50 of 1.8 nM, 1.9 nM and 1.3 nM, respectively. Resatorvid downregulates expression of TLR4 downstream signaling molecules MyD88 and TRIF. Resatorvid inhibits autophagy.
Storage Conditions
3 years -20°C powder
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TAF-446-1 1 mL
Texas Red Conjugated Goat Affinity Purified Antibody to Mouse IgA
Sign In for Pricing
View Details 
BNC740758-100 1x 100 µL
Human IgG Immunoglobulin (ICO-97), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
TRC-G837962-10MG 10 mg
Guanosine 3’,5’-Cyclic-13C,15N2 Monophosphate
Sign In for Pricing
View Details 
BNC743648-500 1x 500 µL
SOX2 (Embryonic Stem Cell Marker) (rSOX2/1791), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details