AMG 232 (KRT-232)
Product Specifications
CAS Number
1352066-68-2
Synonyms
Navtemadlin
Target
MDM2/MDMX
Applications
Apoptosis
Molecular Formula
C28H35Cl2NO5S
Additionnal Information
AMG 232 (Navtemadlin) is a potential, selective inhibitor of the MDM2–p53 interaction, with an IC50 of 0.6 nM and binds to MDM2 with a Kd of 0.045 nM. It also demonstrated antitumor activity in vivo in a variety of tumor types with different genetic backgrounds.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
OM617016 96 Strip Well
Bovine Uveal autoantigen with coiled-coil domains and ankyrin repeats ELISA Kit
Sign In for Pricing
View Details 
orb2831125-01 20 µg
Recombinant RUBV Spike glycoprotein E1 Protein, N-His
Sign In for Pricing
View Details orb2831125-02 50 µg
Recombinant RUBV Spike glycoprotein E1 Protein, N-His
Sign In for Pricing
View Details orb2831125-03 100 µg
Recombinant RUBV Spike glycoprotein E1 Protein, N-His
Sign In for Pricing
View Details 