CGP 57380
Product Specifications
CAS Number
522629-08-9
Target
MNK
Applications
MAPK
Smiles
C1=CC (=CC=C1NC2=C3C (=NC=NC3=NN2) N) F
Molecular Formula
C11H9FN6
Additionnal Information
CGP 57380 is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like kinases. CGP 57380 upregulates β-catenin and potentiates radiation-induced apoptosis.
Storage Conditions
2 years -80 in solvent
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