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ISRIB (trans-isomer)

Product Specifications

CAS Number

1597403-47-8

Target

PERK

Applications

Apoptosis

Smiles

C1CC (CCC1NC (=O) COC2=CC=C (C=C2) Cl) NC (=O) COC3=CC=C (C=C3) Cl

Molecular Formula

C22H24Cl2N2O4

Additionnal Information

ISRIB (trans-isomer), the trans-isomer of ISRIB, is a potent and selective PERK inhibitor with IC50 of 5 nM and does not have global effects on translation, transcription, or mRNA stability in non-stressed cells.

Storage Conditions

2 years -80 in solvent

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