ISRIB (trans-isomer)
Product Specifications
CAS Number
1597403-47-8
Target
PERK
Applications
Apoptosis
Smiles
C1CC (CCC1NC (=O) COC2=CC=C (C=C2) Cl) NC (=O) COC3=CC=C (C=C3) Cl
Molecular Formula
C22H24Cl2N2O4
Additionnal Information
ISRIB (trans-isomer), the trans-isomer of ISRIB, is a potent and selective PERK inhibitor with IC50 of 5 nM and does not have global effects on translation, transcription, or mRNA stability in non-stressed cells.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNUB2843-100 1x 100 µL
SIGLEC1 / CD169 / Sialoadhesin (HSn 7D2), 0.2mg/mL
Sign In for Pricing
View Details 
17623-AAT 200 Tests
Helixyte™ Green Fluorimetric ssDNA Quantitation Kit *Optimized for Microplate Readers*
Sign In for Pricing
View Details 
BNC683113-500 1x 500 µL
TIM3 / HAVCR2 / CD366 (Effector T-Cell Marker) (TIM3/3113), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details