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Aloxistatin (E64d)

Product Specifications

CAS Number

88321-09-9

Synonyms

E-64d

Target

Cysteine Protease

Applications

Proteases

Smiles

CCOC (=O) C1C (O1) C (=O) NC (CC (C) C) C (=O) NCCC (C) C

Molecular Formula

C17H30N2O5

Additionnal Information

Aloxistatin (E64d) is an irreversible and membrane-permeable cysteine protease inhibitor with blood platelet aggregation inhibiting activity. The cysteine protease cathepsin L is required for SARS-CoV-2 viral entry, and aloxistatin treatment reduced cellular entry of SARS-CoV-2 pseudovirions by 92.3%.

Storage Conditions

2 years -80 in solvent

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