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E-64

Product Specifications

CAS Number

66701-25-5

Target

Cysteine Protease

Applications

Proteases

Smiles

CC (C) CC (C (=O) NCCCCN=C (N) N) NC (=O) C1C (O1) C (=O) O

Molecular Formula

C15H27N5O5

Additionnal Information

E-64 is an irreversible and selective cysteine protease inhibitor, and also inhibits papain, calpain, and cathepsins B and H, but not serine proteases or aspartic proteases. The IC50 for papain is 9 nM. E-64 induces oxidative stress and apoptosis in Filarial Parasite.

Storage Conditions

2 years -80 in solvent

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