PF-562271 HCl
Product Specifications
CAS Number
939791-41-0
Target
FAK
Applications
Protein Tyrosine Kinase
Smiles
CN (C1=C (C=CC=N1) CNC2=NC (=NC=C2C (F) (F) F) NC3=CC4=C (C=C3) NC (=O) C4) S (=O) (=O) C.Cl
Molecular Formula
C21H21ClF3N7O3S
Additionnal Information
PF-562271 HCl is the hydrochloride salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs. Phase 1.
Storage Conditions
2 years -80 in solvent
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