What is the catalog number for URMC-099?

The catalog number for URMC-099 is S7343-25mg.

What sizes are available for URMC-099?

URMC-099 is available in the following size(s): 25 mg.

Is URMC-099 in stock?

URMC-099 is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for URMC-099?

URMC-099 is requires dry ice shipping.

Who manufactures URMC-099?

URMC-099 is manufactured by Bimake.

What is the estimated delivery time for URMC-099?

Estimated delivery time for URMC-099 is approximately 15 business day(s), depending on your location.

URMC-099

Product Specifications

CAS Number

1229582-33-5

Target

LRRK2

Applications

Autophagy

Smiles

CN1CCN (CC1) CC2=CC=C (C=C2) C3=CC4=C (NC=C4C5=CC6=C (C=C5) NC=C6) N=C3

Molecular Formula

C27H27N5

Additionnal Information

URMC-099 is an orally bioavailable, brain penetrant mixed lineage kinase (MLK) inhibitor with IC50 of 19 nM, 42 nM, 14 nM, and 150 nM, for MLK1, MLK2, MLK3, and DLK, respectively, and also inhibits LRRK2 activity with IC50 of 11 nM. URMC-099 also inhibits ABL1 with IC50 of 6.8 nM. URMC-099 induces autophagy.