What is the catalog number for GSK2606414?

The catalog number for GSK2606414 is S7307-50mg.

What sizes are available for GSK2606414?

GSK2606414 is available in the following size(s): 50 mg.

Is GSK2606414 in stock?

GSK2606414 is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for GSK2606414?

GSK2606414 is requires dry ice shipping.

Who manufactures GSK2606414?

GSK2606414 is manufactured by Bimake.

What is the estimated delivery time for GSK2606414?

Estimated delivery time for GSK2606414 is approximately 15 business day(s), depending on your location.

GSK2606414

Product Specifications

CAS Number

1337531-36-8

Target

PERK

Applications

Apoptosis

Smiles

CN1C=C (C2=C (N=CN=C21) N) C3=CC4=C (C=C3) N (CC4) C (=O) CC5=CC (=CC=C5) C (F) (F) F

Molecular Formula

C24H20F3N5O

Additionnal Information

GSK2606414 is an orally available, potent, and selective PERK inhibitor with IC50 of 0.4 nM, displaying at least 100-fold selectivity over the other EIF2AKs assayed. GSK2606414 impairs GANT-61 induced autophagy in NB cells with MYCN amplification. GSK2606414 exacerbates ER stress-induced apoptosis in HCT116 cells while reduces the apoptosis in SIL1 KD HeLa cells.