Dorsomorphin 2HCl
Product Specifications
CAS Number
1219168-18-9
Synonyms
BML-275 2HCl, Compound C 2HCl
Target
AMPK
Applications
PI3K/Akt/mTOR
Smiles
C1CCN (CC1) CCOC2=CC=C (C=C2) C3=CN4C (=C (C=N4) C5=CC=NC=C5) N=C3.Cl.Cl
Molecular Formula
C24H25N5O.2HCl
Additionnal Information
Dorsomorphin 2HCl is a potent, reversible, selective AMPK inhibitor with Ki of 109 nM in cell-free assays, exhibiting no significant inhibition of several structurally related kinases including ZAPK, SYK, PKCθ, PKA, and JAK3. Also inhibits type I BMP receptor activity. Dorsomorphin induces autophagy in cancer cell line.
Storage Conditions
2 years -80 in solvent
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