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Dorsomorphin 2HCl

Product Specifications

CAS Number

1219168-18-9

Synonyms

BML-275 2HCl, Compound C 2HCl

Target

AMPK

Applications

PI3K/Akt/mTOR

Smiles

C1CCN (CC1) CCOC2=CC=C (C=C2) C3=CN4C (=C (C=N4) C5=CC=NC=C5) N=C3.Cl.Cl

Molecular Formula

C24H25N5O.2HCl

Additionnal Information

Dorsomorphin 2HCl is a potent, reversible, selective AMPK inhibitor with Ki of 109 nM in cell-free assays, exhibiting no significant inhibition of several structurally related kinases including ZAPK, SYK, PKCθ, PKA, and JAK3. Also inhibits type I BMP receptor activity. Dorsomorphin induces autophagy in cancer cell line.

Storage Conditions

2 years -80 in solvent

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