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Osimertinib (AZD9291)

Product Specifications

CAS Number

1421373-65-0

Synonyms

Mereletinib

Target

EGFR

Applications

Protein Tyrosine Kinase

Smiles

CN1C=C (C2=CC=CC=C21) C3=NC (=NC=C3) NC4=C (C=C (C (=C4) NC (=O) C=C) N (C) CCN (C) C) OC

Molecular Formula

C28 H33 N7 O2

Additionnal Information

Osimertinib (AZD9291) is an oral, irreversible, and mutant-selective EGFR inhibitor with IC50 of 12.92, 11.44 and 493.8 nM for Exon 19 deletion EGFR, L858R/T790M EGFR, and WT EGFR in LoVo cells, respectively. Phase 3.

Storage Conditions

2 years -80 in solvent

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