Osimertinib (AZD9291)
Product Specifications
CAS Number
1421373-65-0
Synonyms
Mereletinib
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
CN1C=C (C2=CC=CC=C21) C3=NC (=NC=C3) NC4=C (C=C (C (=C4) NC (=O) C=C) N (C) CCN (C) C) OC
Molecular Formula
C28 H33 N7 O2
Additionnal Information
Osimertinib (AZD9291) is an oral, irreversible, and mutant-selective EGFR inhibitor with IC50 of 12.92, 11.44 and 493.8 nM for Exon 19 deletion EGFR, L858R/T790M EGFR, and WT EGFR in LoVo cells, respectively. Phase 3.
Storage Conditions
2 years -80 in solvent
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