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PFI-2 HCl

Product Specifications

CAS Number

1627607-87-7

Target

Histone Methyltransferase

Applications

Epigenetics

Smiles

C1CCN (C1) C (=O) C (CC2=CC (=CC=C2) C (F) (F) F) NS (=O) (=O) C3=CC4=C (CNCC4) C (=C3) F.Cl

Molecular Formula

C23H25F4N3O3S.HCl

Additionnal Information

PFI-2 is a potent, selective, and cell-active lysine methyltransferase SETD7 inhibitor with Ki (app) and IC50 of 0.33 nM and 2 nM, 1000-fold selectivity over other methyltransferases and other non-epigenetic targets.

Storage Conditions

2 years -80 in solvent

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