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SGC-CBP30

Product Specifications

CAS Number

1613695-14-9

Target

Epigenetic Reader Domain

Applications

Epigenetics

Smiles

CC1=C (C (=NO1) C) C2=CC3=C (C=C2) N (C (=N3) CCC4=CC (=C (C=C4) OC) Cl) CC (C) N5CCOCC5

Molecular Formula

C28H33ClN4O3

Additionnal Information

SGC-CBP30 is a potent CREBBP/EP300 inhibitor with IC50 of 21 nM and 38 nM in cell-free assays, respectively. Exhibits 40-fold and 250-fold selectivity for CBP over the first BRD of BRD4 (BRD4 (1) ) and BRD4 (2) respectively.

Storage Conditions

2 years -80 in solvent

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