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RepSox (E-616452)

Product Specifications

CAS Number

446859-33-2

Synonyms

SJN 2511, ALK5 Inhibitor II

Target

TGF-beta/Smad

Applications

TGF-beta/Smad

Smiles

CC1=NC (=CC=C1) C2=C (C=NN2) C3=NC4=C (C=C3) N=CC=C4

Molecular Formula

C17H13N5

Additionnal Information

RepSox (E-616452, SJN 2511, ALK5 Inhibitor II) is a potent and selective inhibitor of the TGFβR-1/ALK5 with IC50 of 23 nM and 4 nM for ATP binding to ALK5 and ALK5 autophosphorylation in cell-free assays, respectively.

Storage Conditions

2 years -80 in solvent

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