RepSox (E-616452)
Product Specifications
CAS Number
446859-33-2
Synonyms
SJN 2511, ALK5 Inhibitor II
Target
TGF-beta/Smad
Applications
TGF-beta/Smad
Smiles
CC1=NC (=CC=C1) C2=C (C=NN2) C3=NC4=C (C=C3) N=CC=C4
Molecular Formula
C17H13N5
Additionnal Information
RepSox (E-616452, SJN 2511, ALK5 Inhibitor II) is a potent and selective inhibitor of the TGFβR-1/ALK5 with IC50 of 23 nM and 4 nM for ATP binding to ALK5 and ALK5 autophosphorylation in cell-free assays, respectively.
Storage Conditions
2 years -80 in solvent
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