What is the catalog number for BIO?

The catalog number for BIO is S7198-10mM/1mL.

What sizes are available for BIO?

BIO is available in the following size(s): 10 mM/1mL.

BIO is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for BIO?

BIO is requires dry ice shipping.

What is the estimated delivery time for BIO?

Estimated delivery time for BIO is approximately 15 business day(s), depending on your location.

BIO

Product Specifications

CAS Number

667463-62-9

Synonyms

GSK-3 Inhibitor IX, 6-bromoindirubin-3-oxime, 6-Bromoindirubin-3'-oxime, MLS 2052

Target

GSK-3

Applications

PI3K/Akt/mTOR

Smiles

C1=CC=C2C (=C1) C (=C (N2) C3=C (NC4=C3C=CC (=C4) Br) O) N=O

Molecular Formula

C16H10BrN3O2

Additionnal Information

BIO (GSK-3 Inhibitor IX, 6-bromoindirubin-3-oxime, 6-Bromoindirubin-3'-oxime, MLS 2052) is a specific inhibitor of GSK-3 with IC50 of 5 nM for GSK-3α/β in a cell-free assay, shows >16-fold selectivity over CDK5, also a pan-JAK inhibitor with IC50 of 30 nM for Tyk2. BIO induces apoptosis in human melanoma cells.