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Prexasertib HCl (LY2606368)

Product Specifications

CAS Number

1234015-54-3

Target

Chk

Applications

Cell Cycle

Smiles

COC1=C (C (=CC=C1) OCCCN) C2=CC (=NN2) NC3=NC=C (N=C3) C#N.Cl.Cl

Molecular Formula

C18H19N7O2.2HCl

Additionnal Information

Prexasertib (LY2606368) is an ATP-competitive CHK1 inhibitor with a Ki value of 0.9 nmol/L. For CHK2 and RSK, its IC50 values are 8 nM and 9 nM respectively in cell-free assay.

Storage Conditions

2 years -80 in solvent

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