Spebrutinib (AVL-292)
Product Specifications
CAS Number
1202757-89-8
Synonyms
CC-292
Target
BTK
Applications
Protein Tyrosine Kinase
Smiles
COCCOC1=CC=C (C=C1) NC2=NC=C (C (=N2) NC3=CC (=CC=C3) NC (=O) C=C) F
Molecular Formula
C22H22FN5O3
Additionnal Information
Spebrutinib (AVL-292) is a covalent, orally active, and highly selective BTK inhibitor with IC50 of <0.5 nM, displaying at least 1400-fold selectivity over the other kinases assayed. Phase 1.
Storage Conditions
2 years -80 in solvent
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