Setanaxib (GKT137831)
Product Specifications
CAS Number
1218942-37-0
Synonyms
GKT831
Target
NADPH-oxidase
Applications
Immunology & Inflammation
Smiles
CN1C (=O) C=C2C (=C1C3=CC (=CC=C3) N (C) C) C (=O) N (N2) C4=CC=CC=C4Cl
Molecular Formula
C21H19ClN4O2
Additionnal Information
Setanaxib (GKT137831, GKT831) is a potent, dual NADPH oxidase NOX1/NOX4 inhibitor with Ki of 110 nM and 140 nM, respectively. Treatment with GKT137831 suppresses reactive oxygen species (ROS) production. GKT137831 partly inhibits ferroptosis.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6469901-01 0.2 mL
COL18A1, NT (Collagen alpha-1(XVIII) Chain, Endostatin) (Azide free) (HRP)
Sign In for Pricing
View Details MBS6469901-02 5x 0.2 mL
COL18A1, NT (Collagen alpha-1(XVIII) Chain, Endostatin) (Azide free) (HRP)
Sign In for Pricing
View Details LKU600697 96 Tests
Proprotein Convertase Subtilisin/Kexin Type 4 (PCSK4) Magnetic Luminex Assay Kit
Sign In for Pricing
View Details