GSK343
Product Specifications
CAS Number
1346704-33-3
Target
Histone Methyltransferase
Applications
Epigenetics
Smiles
CCCC1=C (C (=O) NC (=C1) C) CNC (=O) C2=C3C=NN (C3=CC (=C2) C4=CC (=NC=C4) N5CCN (CC5) C) C (C) C
Molecular Formula
C31H39N7O2
Additionnal Information
GSK343 is a potent and selective EZH2 inhibitor with IC50 of 4 nM in a cell-free assay, showing 60 fold selectivity against EZH1, and >1000 fold selectivity against other histone methyltransferases. GSK343 induces autophagy.
Storage Conditions
2 years -80 in solvent
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