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Mdivi-1

Product Specifications

CAS Number

338967-87-6

Synonyms

Mitochondrial division inhibitor 1

Target

Dynamin

Applications

Cytoskeletal Signaling

Smiles

COC1=C (C=C (C (=C1) N2C (=O) C3=CC=CC=C3NC2=S) Cl) Cl

Molecular Formula

C15H10Cl2N2O2S

Additionnal Information

Mdivi-1 (Mitochondrial division inhibitor 1) is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 μM. Mdivi-1 attenuates mitophagy and enhances apoptosis.

Storage Conditions

2 years -80 in solvent

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