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Abemaciclib mesylate

Product Specifications

CAS Number

1231930-82-7

Synonyms

LY2835219 mesylate

Target

CDK

Applications

Cell Cycle

Smiles

CCN1CCN (CC1) CC2=CN=C (C=C2) NC3=NC=C (C (=N3) C4=CC5=C (C (=C4) F) N=C (N5C (C) C) C) F.CS (=O) (=O) O

Molecular Formula

C27H32F2N8.CH4O3S

Additionnal Information

Abemaciclib mesylate is a potent and selective inhibitor of CDK4 and CDK6 with IC50 of 2 nM and 10 nM in cell-free assays, respectively. Phase 3.

Storage Conditions

2 years -80 in solvent

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