LDN-212854

Product Specifications

CAS Number

1432597-26-6

Synonyms

BMP Inhibitor III

Target

TGF-beta/Smad

Applications

TGF-beta/Smad

Smiles

C1CN (CCN1) C2=CC=C (C=C2) C3=CN4C (=C (C=N4) C5=C6C=CC=NC6=CC=C5) N=C3

Molecular Formula

C25 H22 N6

Additionnal Information

LDN-212854 (BMP Inhibitor III) is a potent and selective BMP receptor inhibitor with IC50 of 1.3 nM for ALK2, about 2-, 66-, 1641-, and 7135-fold selectivity over ALK1, ALK3, ALK4, and ALK5, respectively.

Storage Conditions

2 years -80 in solvent

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