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LGK-974

Product Specifications

CAS Number

1243244-14-5

Synonyms

NVP-LGK974, WNT974

Target

PORCN

Applications

Cytoskeletal Signaling

Smiles

CC1=CC (=CN=C1C2=CC (=NC=C2) C) CC (=O) NC3=NC=C (C=C3) C4=NC=CN=C4

Molecular Formula

C23H20N6O

Additionnal Information

LGK-974 (NVP-LGK974, WNT974) is a potent and specific PORCN inhibitor, and inhibits Wnt signaling with IC50 of 0.4 nM in TM3 cells. Phase 1.

Storage Conditions

2 years -80 in solvent

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